Australasian Diabetes Data Network (ADDN)
The ADDN project commenced in 2012 as a joint initiative between the Australia and New Zealand Society for Paediatric Endocrinology and Diabetes (ANZSPED) and Juvenile Diabetes Research Foundation (JDRF) Australia. The first phase of ADDN established a secure and centralised data repository hosted by the University of Melbourne, holding de-identified longitudinal demographic and clinical data for more than 5,000 children and adolescents with diabetes. The overall aim of the ADDN project is to facilitate research and improve the health of people with diabetes.
In 2016 the Australian Diabetes Society (ADS) joined ANZSPED and JDRF Australia for the second phase of ADDN which expanded the number of paediatric centres and extended recruitment to include adult centres. With this, ADDN extended its data capture and provide richer and more complete information about the natural history, clinical progression and most effective treatment regimens for all people living with type 1 diabetes. In Phase two, the focus shifted from development to improving data integrity, quality and overseeing use of the data for research.
Data collected by ADDN has enabled, for the first time, to conduct longitudinal research across paediatric and adult diabetes services. It will be possible to identify treatment strategies for type 1 diabetes that provide the best long-term outcomes, as well as enabling researchers to determine whether patients are eligible for clinical trials. ADDN publishes benchmarking reports twice annually to support participating centres in their quality improvement efforts.
ADDN will commence Phase 3 in the second half of 2021. The appointment of a Medical Director will lead ADDN’s strategic plan to capture data on all young people with diabetes and to understand how to improve treatment and management of type 1 diabetes over the lifetime.
Data are accessible to researchers within strict ethical and governance boundaries.
To find out more about ADDN we encourage the wider research community to visit the ADDN website HERE
- Five heterogeneous HbA1c trajectories from childhood to adulthood in youth with type 1 diabetes from three different continents: A group-based modelling approach.
Pediatr Diabetes. 2019 Nov; 20(7):920-931. Epub 2019 Aug 28.
Clements MA, Schwandt A, Donaghue KC, Miller K, Lück U, Couper JJ, Foster N, Schröder C, Phelan H, Maahs D, Prinz N, Craig ME; Australasian Diabetes Data Network (ADDN) Study Group, the T1D Exchange Clinic Network (T1DX), and the German/Austrian/Luxembourgian Diabetes-Patienten-Verlaufsdokumentation (DPV) initiative.xz
https:// doi: 10.1111/pedi.12907
- Longitudinal trajectories of BMI z-score: An international comparison of 11,513 Australian, American and German/Austrian/Luxembourgian youth with type 1 diabetes. Pediatr Obes. 2020 Feb;15(2):e12582. Epub 2019 Nov 5
Phelan H, Foster NC, Schwandt A, Couper J, Willi S, Kroschwald P, Jones TW, Wu M, Steigleder-Schweiger C, Craig ME, Maahs DM and Prinz N on behalf of the Australasian Diabetes Data Network (ADDN), the T1D Exchange Clinic Network (T1DX), and the Prospective Diabetes Follow-up Registry (DPV) initiative.
- Temporal trends in diabetic ketoacidosis at diagnosis of paediatric type 1 diabetes between 2006 and 2016: results from 13 countries in three continent. Diabetologia 2020 May 8
Cherubini V, Grimsman JM, Åkesso k, Birkebæ NH, Cinek O, Dovč K, Gesuita R, Gregory JW, Hanas R, Hofer SE, Holl RW, Jefferies C, Joner G, King BR, Mayer-Davis EJ, Peña AS, Rami-Merhar B, Schierloh U, Skrivarhaug T, Sumnik Z, Svensson J, Warner JT, Bratina N, Dabelea D.
- Hemoglobin A1c Patterns of Youth with Type 1 Diabetes 10 Years Post-Diagnosis from 3 Continents. Diabetes 2020 Jun; 69(Supplement 1).
Sherr JL, Schwandt A, Phelan H, Clements MA, Holl RW, Benitez-Aguirre PZ, Miller KM, Woelfle J, Dover T, Maah DM, Fröhlich-Reiterer E, Craig ME.
- Determinants of cardiovascular risk in 7,000 youth with type 1 diabetes in the Australasian Diabetes Data Network. J Clin Endocrinol Metab. 2021 Jan 1;106(1):133-142. doi: 10.1210/clinem/dgaa727
Couper JJ, Jones TW, Chee M, Barrett HL, Bergman P, Cameron F, Craig ME, Colman P, Davis EE, Donaghue KC, Fegan PG, Hamblin PS, Holmes-Walker DJ, Jefferies C, Johnson S, Mok MT, King BR, Sinnott R, Ward G, Wheeler BJ, Zimmermann A, Earnest A.
https://doi.org/10.1210/clinem/dgaa727. PMID: 33120421
- Type 2 diabetes in children and adolescents across Australia and New Zealand: a 6 year audit from The Australasian Diabetes Data Network (ADDN). Pediatr. Diabetes 2020 Dec 8:
Karissa L, Craig ME, Donaghue KC, Maguire A, Benitez-Aguirre PZ and the ADDN Study Group
- Glycaemic outcomes in Australasian children and adults with Type 1 Diabetes: failure to meet targets across the age spectrum. Intern Med J. 2021 Jun 18.
Holmes-Walker DJ, Abraham MB, Chee M, Jones TW and ADDN Group
- Hemoglobin A1c Patterns of Youth With Type 1 Diabetes 10 Years Post Diagnosis From 3 Continents Pediatrics. 2021 Jul 27;e2020048942
Sherr JL, Schwandt A, Phelan H, Clements MA, Holl RW, Benitez-Aguirre PZ, Miller KM, Woelfle J, Dover T, Maahs DM, Fröhlich-Reiterer E, Craig ME.
https://doi.org/10.1542/peds.2020-048942 Online ahead of print.